EPISODE 67
Feb 11, 2026

bending the chronic disease curvey with sean duffy

Not many digital health companies go public. And even fewer do so with a model designed to fix what’s truly broken in U.S. healthcare: episodic, fragmented care that fails to support the behavior change required to manage chronic disease. Omada Health CEO Sean Duffy joins Claudia to discuss the company’s journey from scrappy startup to public company—and his biggest ambition for the future: bending the nation’s chronic disease curve, both in cost and in human suffering. 

Claudia and Sean talk about:
  • Omada’s “full stack” approach to chronic care 
  • What Omada’s IPO signals for digital health’s future
  • Why GLP1s are a catalyst not a shortcut
  • How employers have quietly driven healthcare innovation 

Sean says for Omada to actually shift what consumers pay out of pocket every month for their premiums we need to make big changes:

“Affordability is the thing… That's the burden we're bearing as a country… And so, the only way to bring down healthcare costs are completely transformed care models. That's the only way… Thank goodness we're at a moment where those models are being supported and being scaled nationally. Thank goodness we're at a moment where technologies like AI can help add even more efficiency and help scale… Our only way out are different care models [that] leverage new technologies.”

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ABOUT OUR GUEST

Sean Duffy co-founded Omada in 2011 with the aim of merging medical trends and cutting edge technology to revolutionize health care of chronic disease as we know it. Today, he proudly serves as CEO and has been instrumental in steering Omada toward global recognition, such as being hailed a potential “medical triumph” by The New York Times, and one of Fast Company’s 50 most innovative companies in the world. A longtime devotee of healthcare and technology, Sean also founded a largely automated lifestyle business around Excel Everest, the interactive Microsoft Excel training tool he created. He formerly covered healthcare innovation as writer and editor for Medgadget, a popular medical technology blog. As CEO of Omada, Sean cares deeply about honing the organization’s exceptional products, values-driven approach to healthcare, and the innovative ways  in which primary care can continue to better humanity. More recently, Sean has been spending more and more of his free time learning how to build and fly first-person view drones.

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